Hamilton’s Digital Syringes are calibrated devices composed of a serialized syringe and a serialized digital electronic holder. A certificate of calibration comes with the unit. A digital readout allows enhanced syringe volume readability, while an adjustable plunger stop assures accurate, reproducible sample injections. The device also reduces the possibility of plunger bending. Suggested uses of the Digital Syringe include standard preparation, sample preparation, GC injection, HPLC partial loop filling, titration, and calibration of gas analyzers. The base unit can be used with Hamilton syringes in the 700, 1700, and 7000 series with nominal volumes between 0.5ul and 500ul.